to Warfarin

• Stop Rivaroxaban
• If continuous AC needed, start Warfarin with parenteral anticoagulant at next scheduled dose

to Heparin (CI)

• Stop Rivaroxaban
• Start CI Heparin without a bolus at next scheduled dose

to LMWH

• Stop Rivaroxaban
• Start LMWH at next scheduled dose

to Dabigatran

• Stop Rivaroxaban
• Start Dabigatran at next scheduled dose

to Apixaban

• Stop Rivaroxaban
• Start Apixaban at time of next scheduled dose

to Rivaroxaban

• N/A

to Edoxoban

• Stop Rivaroxaban
• Start Edoxaban at time of next scheduled dose

*Note: Dabigatran, Rivaroxaban, Edoxaban, and Apixaban affect the INR; measuring the INR during coadministration with warfarin therapy may not be useful for determining an appropriate dose of warfarin. To minimize this effect, check INR at trough level of respective medication