Baxalta Extended t1/2 Recombinant Pegylated ProteinHALF LIFE (hours):Adults: 14.69 3rd Gen (FLC) Peds:1 – 5 yrs: 11.86 – 11 yrs: 12.412 – 18 yrs: 13.43 Dosing Calculation # Units = weight (kg) X % correction* X VD (0.5)*Written as Whole Number (50%=50) Topic Dose IU/kg (% correction) <12 yrs ≥12 yrs Prophylaxis 55-70 (110- 140%) 2 x/wk 40-50 (80- 100%) 2 […]
Pfizer Standard t1/2 HALF LIFE (hours): Recombinant Adult: 11.2 + 5Peds: 8 + 2.4 3rd Gen (BDD) *Per IHTC dosing:Half-life for all FVIII Standard t1/2 products: ~12 hours Dosing Calculation # Units = weight (kg) X % correction* X VD (0.5)*Written as Whole Number (50%=50) Topic Dose IU/kg (% correction) Prophylaxis 3x/week: 25/25/50 (50%/50%/100%) Minor Bleed 20 (40%) Major Bleed 40 (80%) Transfer Device […]
Novo Nordisk Standard t1/2HALF LIFE (hours): Recombinant Adult: 11-12Peds: 7.7-10 3rd Gen (BDT) *Per IHTC dosing:Half-life for all FVIII Standard t1/2 products: ~12 hours Dosing Calculation # Units = weight (kg) X % correction* X VD (0.5)*Written as Whole Number (50%=50) Topic Dose IU/kg (% correction) Prophylaxis 3x/week: 25/25/50 (50%/50%/100%) Minor Bleed 20 (40%) Major Bleed 40 (80%) Transfer Device Storage Refrigerate at […]
Baxalta Standard t1/2HALF LIFE (hours): Recombinant Adult: 12Peds: 8.7-11.2 3rd Gen (FLC) *Per IHTC dosing:Half-life for all FVIII Standard t1/2 products: ~12 hours Dosing Calculation # Units = weight (kg) X % correction* X VD (0.5)*Written as Whole Number (50%=50) Topic Dose IU/kg (% correction) Prophylaxis 3x/week: 25/25/50 (50%/50%/100%) Minor Bleed 20 (40%) Major Bleed 40 (80%) Transfer Device Storage Refrigerate at 2 […]
