Baxalta Standard t1/2HALF LIFE (hours): Recombinant Adult: 12Peds: 8.7-11.2 3rd Gen (FLC) *Per IHTC dosing:Half-life for all FVIII Standard t1/2 products: ~12 hours Dosing Calculation # Units = weight (kg) X % correction* X VD (0.5)*Written as Whole Number (50%=50) Topic Dose IU/kg (% correction) Prophylaxis 3x/week: 25/25/50 (50%/50%/100%) Minor Bleed 20 (40%) Major Bleed 40 (80%) Transfer Device Storage Refrigerate at 2 […]
CSL Behring Standard t1/2HALF LIFE (hours): 17.5 Plasma-derived *Per IHTC dosing:
Half-life for all PD FVIII products: ~12 hours Dosing Calculation # Units = weight (kg) X % correction* X VD (0.5)*Written as Whole Number (50%=50) Topic Dose IU/kg (% correction) Prophylaxis 3x/week: 25/25/50 (50%/50%/100%) Minor Bleed 20 (40%) Major Bleed 40 (80%) Transfer Device Storage Refrigerate […]
STAQ Pharmaceuticals Standard t1/2
HALF LIFE (hours): 8-12
*Same as endogenous FVIII Dosing Calculation Topic Dose (150 mcg/spray) <50 kg 1 spray ≥50 kg 2 sprays Notes For mild FVIII deficiency only. Fluid restriction. Do not use in children <2 years of age. Use caution in pregnant women during labor and delivery, patients with cardiac […]
Grifols Standard t1/2 Plasma-derived Contains VWF HALF LIFE (hours): 16.12 VWF:FVIII = < 1:1 *Per IHTC dosing:
Half-life for all PD FVIII products: ~ 12 Dosing Calculation # Units = weight (kg) X % correction* X VD (0.5)*Written as Whole Number (50%=50) Topic Dose FVIII IU/kg (% correction) Prophylaxis 3x/week: 25/25/50 (50%/50%/100%) Minor Bleed 20 (40%) Major Bleed 40 (80%) Transfer Device Storage […]
CSL Behring Standard t1/2 Plasma-derived Contains VWF HALF LIFE (hours): 12.2 VWF:FVIII = ~ 2:1 *Per IHTC dosing:
Half-life for all PD FVIII products: ~ 12 hours Dosing Calculation # Units = weight (kg) X % correction* X VD (0.5)
*Written as Whole Number (50%=50) Topic Dose FVIII IU/kg (% correction) Prophylaxis 3x/week: 25/25/50 (50%/50%/100%) Minor Bleed 20 (40%) Major Bleed 40 (80%) Notes […]
Grifols Standard t1/2
Plasma-derived Contains VWF HALF LIFE (hours): 17.9 VWF:FVIII = 1.3:1 *Per IHTC dosing:
Half-life for all PD FVIII products: ~12 hours Dosing Calculation # Units = weight (kg) X % correction* X VD (0.5)*Written as Whole Number (50%=50) Topic Dose FVIII IU/kg (% correction) Prophylaxis 3x/week: 25/25/50 (50%/50%/100%) Minor Bleed 20 (40%) Major Bleed 40 (80%) Notes FDA 8/1978 […]